botulino1The aging starts when the skin, reached the full morphological and functional maturity, shows the first signs of decay, which may arise at any age especially with the appearance of wrinkles, sagging of the dermis or alterations of the shape of the face.
The processing of such alterazionisi mainly deals with stimulating the dermis, improving cell turnover and stimulate the fibroblasts in the dermis in order to increase the ‘elastin and collagen, filling depressed areas, optimizing the increase of’ hyaluronic acid and other elements such as glucosoaminoglicani. And ‘also crucial to fight the formation of free radicals, cell metabolism products that accentuate skin aging. The Bio-stimulation is therefore a medical-aesthetic treatment to recover and maintain youthful skin, as well as to prevent aging, through the reconstruction / reorganization of skin texture; the procedure improves elasticity and firmness of the skin tissue, visibly increases skin tone and counteracts the action of free radicals.
The biostimulation determines: immediate action of the lure water in the tissues (it is the most visible effect in the first treatment with the result of the stretch fabrics); the stimulation of fibroblasts in the number and in production of larger amounts of collagen (an action that requires a time of about 80 – 90 days from the first infiltration necessary for the achievement of adequate active concentrations); Action anti radicals, produced by the countless pollutants, stressors, food and not least from solar radiation.


After application of a mixture of local anesthetic cream for 10 minutes and disinfection of the skin, we proceed to the release of the useful substances, immediately below the epidermis of the wrinkle with a disposable thin needle. The total duration does not exceed 15 minutes. Immediately after the treatment you can resume normal professional and family life. At the end of a residual treatment for a few hours a slight swelling (hives) in the injection sites. Although rare, it is possible the presence in places of tiny spontaneous bruising resolution in 24-48 hours. The substances used shall be of tissue regeneration properties and stimulate the fibroblast in its functions. The body, therefore, thanks to the availability of the necessary constituents will be able to reactivate the local metabolic processes and save energy for the synthesis of collagen and elastin. Result: increase in cell renewal and tissue rejuvenation.
What are the products that are typically used for bio-stimulation
• low density hyaluronic acid (E ‘the fundamental and essential element for the final effect)
• precursors of amino acids collagen, elastin and glycosaminoglycans
• vitamins
• PDRN (polydeoxyribonucleotide)
these are the substances that have been shown to have a scientific rationale supporting the regenerative and secretory capacity of fibroblasts and exerting anti-radical action.

Where and when

Injections into the facial skin thickness and also the neck possibly are done with a very fine needle and are generally well tolerated.
Many patients carry sessions of bio-stimulation with hyaluronic acid before summer vacation or winter holiday in order to consume the product during the same and not have so photoaging consuming their natural hyaluronic acid: this is a new concept of active photoprotection is coming in Italy from the United States.

What is the difference between a bio-stimulation and treatment with a filler

The filler is a filler treatment (of ‘English to fill = fill) in the sense that injecting hyaluronic acid or other substances in the form of gels, lifting the bottom of the wrinkle. With bio-stimulation, using a drug that is a precursor of collagen and hyaluronic acid and has remarkable moisturizing power that water lure that in the long run tends to regenerate the bottom of the wrinkle.


The skin will be more fresh, soft, smooth. It restores the harmony of face shapes. Roughness and imperfections, caused by the action of time, will be improved and smoothed out. The results are immediate. Since the causes of skin aging due to sun and all ‘action of time can not be stopped, it is important to understand that a single treatment is not enough to keep the skin healthy and beautiful over time.