iperidrosi ascellareThis term defines the excessive sweating in the armpit level. This condition that causes embarrassment is actually very easy to treat. There are remedies both medical and surgical. Both are intended to stop the pathophysiological mechanism that causes a localized excessive sweating armpits, without however interrupting the physiological temperature control mechanism of sweating.

Botulinum toxin

Injecting in a completely painless botulinum toxin under the skin of the region to be treated, decreases the stimulation of the sympathetic nervous system (the one active in situations of anxiety, stress, danger, embarrassment, agitation ..) on the sweat glands, which secrete therefore less and more regularly. Dr. Grassetti is co-author of a randomized double-blind study performed in Shanghai and published in the scientific journal of the American Society of Aesthetic Surgery, which shows that the botulinum inhibits not only the production of sweat, but also excess sebum .

The treatment for axillary hyperhidrosis surgery lasts 30 minutes, does not require local anesthesia, it begins to act after a week and should be repeated once or twice a year depending on individual factors.

Contraindications to treatment with botulinum toxin

It should be avoided in patients with myasthenia gravis or who have undergone previous surgery to the armpit, women who are pregnant or breastfeeding, allergic to botulinum toxin and human albumin, subjects treated with aminoglycoside or quinolone antibiotics or with other agents that interfere with neuromuscular transmission (spectinomycin, muscle relaxants tubocurarinici).


There are many more or less invasive methods to block the adrenergic impulses iperstimolano axillary glands to sweat secretion. Most of them are invasive (sympathectomy), or induces against un’ipersudorazione compensatory in other parts of the body like the back, chest and hands.

The most recently used technique is a sort of very superficial liposuction armpits, which mechanically denerva a large part of the sweat glands, resulting in a reduction of 50-70% of the adrenergic sweating or to that which occurs in the agitation or embarrassing moments.

The treatment is performed under local anesthesia with sedation through the microaccessi in the armpit and you can return to normal after 1-2 weeks. During this period must wear a elastocompressiva band to prevent the formation of seromas and swelling; also you have to start 5-6 days after the Physiotherapy and massage to prevent painful scar retractions and “sense of shock” up the arm.

Possible bruising, which resolves completely within 1-2 weeks.


Before undergoing any treatment to cure axillary hyperhidrosis, it is mandatory to exclude all causes that may be secondary to other conditions such as hyperthyroidism, hypoglycemia, obesity, hormonal disorders, antidepressants, pheochromocytoma, spinal cord diseases.